Fuel Smart would help, but that's just a drop in the bucket.
I would expect that any sustained high oil prices will start to weed out a few of the already weaker players.
YX is still on thin ice, as is F9. They might make it since they operate in places not traditionally impacted by LCC fares.
But Skybus? Toast. Spirit? Dunno... PA3? Let's home there's not a PA4.
I also think you're going to see a lot of one way flights to exotic places like ROW, MHV, VCV, IGM, MZJ and YUM. Pickle a few aircraft in case oil drops, and part out the rest.
Perhaps it's time to take a machete to the DFW schedule and drop down to 6 and 7 flights per day into most spoke markets, as opposed to 8 and 9. Assuming none of that traffic spills, that will drive load factors higher.